BPH Treatment Options
Comprehensive Guide to Enlarged Prostate Treatment
Understanding Benign Prostatic Hyperplasia (BPH)
Benign Prostatic Hyperplasia (BPH) is a common condition affecting men as they age, characterized by the non-cancerous enlargement of the prostate gland. As the prostate grows, it can compress the urethra and cause bothersome urinary symptoms that significantly impact quality of life.
Common BPH Symptoms
- Frequent urination, especially at night (nocturia)
- Difficulty starting urination
- Weak or interrupted urine stream
- Feeling of incomplete bladder emptying
- Sudden urgency to urinate
- Straining during urination
- Dribbling at the end of urination

Comparison showing normal prostate vs. enlarged prostate (BPH)
Treatment Options Overview
Medications
First-line treatment for mild to moderate symptoms. Includes alpha-blockers and 5-alpha reductase inhibitors.
- Pros: Non-invasive, reversible
- Cons: Ongoing costs, side effects, limited effectiveness
Minimally Invasive Procedures
Advanced treatments like PAE, UroLift, and Aquablation that offer effective results with minimal recovery time.
- Pros: Effective, quick recovery, preserve function
- Cons: May not be suitable for all prostate sizes
Surgical Options
Traditional surgical treatments like TURP for severe symptoms or when other treatments have failed.
- Pros: Highly effective, definitive treatment
- Cons: Longer recovery, higher risk of complications
Detailed Treatment Comparison
1. Medication Therapy
Alpha-Blockers
- Examples: Tamsulosin (Flomax), Alfuzosin (Uroxatral), Doxazosin (Cardura)
- How they work: Relax smooth muscle in prostate and bladder neck
- Benefits: Quick symptom relief, well-tolerated by most patients
- Side effects: Dizziness, fatigue, retrograde ejaculation
- Effectiveness: 60-70% of patients experience symptom improvement
5-Alpha Reductase Inhibitors
- Examples: Finasteride (Proscar), Dutasteride (Avodart)
- How they work: Shrink prostate by blocking hormone conversion
- Benefits: Reduce prostate size, prevent progression
- Side effects: Sexual dysfunction, breast tenderness, mood changes
- Timeline: 6-12 months for maximum benefit
2. Minimally Invasive Procedures
Prostate Artery Embolization (PAE)
- Approach: Blocks blood flow to enlarged prostate tissue
- Benefits: Outpatient procedure, rapid recovery, preserved sexual function
- Success rate: 93% of patients experience significant improvement
- Recovery: Same-day discharge, return to activities within 2-3 days
Prostatic Urethral Lift (UroLift)
- Approach: Small implants hold enlarged prostate tissue away from urethra
- Benefits: Preserves sexual function, outpatient procedure
- Limitations: May not be suitable for very large prostates
- Recovery: Minimal downtime, catheter typically not required
Aquablation Therapy
- Approach: Uses high-velocity water jet to remove prostate tissue with robotic precision
- Technology: Real-time ultrasound imaging guides water jet ablation
- Benefits: Precise tissue removal, preserves sexual function, consistent outcomes
- Procedure: Performed under general anesthesia, typically 45-60 minutes
- Recovery: Catheter for 1-3 days, return to activities within 1-2 weeks
- Effectiveness: Significant symptom improvement in 80-85% of patients
- Considerations: Newer technology with growing clinical experience
3. Surgical Treatment Options
Transurethral Resection of Prostate (TURP)
- Approach: Surgical removal of prostate tissue through urethra
- Benefits: Highly effective, gold standard for large prostates
- Limitations: Risk of sexual side effects, longer recovery
- Recovery: 2-6 weeks, catheter required for several days
Laser Surgery (HoLEP, PVP)
- Approach: Laser energy removes or vaporizes prostate tissue
- Benefits: Less bleeding than TURP, shorter hospital stay
- Limitations: Specialized equipment required, learning curve
- Recovery: 1-2 weeks, reduced catheter time
Open Prostatectomy
- Approach: Surgical removal through abdominal incision
- Indications: Very large prostates (>100 grams)
- Benefits: Complete tissue removal, definitive treatment
- Recovery: 4-6 weeks, highest risk of complications
Treatment Comparison Guide
Effectiveness Comparison
Symptom Relief Success Rates:
- PAE: 93% significant improvement
- TURP: 85-95% improvement
- Aquablation: 80-85% improvement
- Medications: 60-70% improvement
- UroLift: 70-80% improvement
- Laser Surgery: 80-90% improvement
Recovery Time Comparison
Return to Normal Activities:
- PAE: 2-3 days
- UroLift: 3-7 days
- Aquablation: 1-2 weeks
- Medications: Immediate (but gradual effect)
- Laser Surgery: 1-2 weeks
- TURP: 2-6 weeks
- Open Surgery: 4-6 weeks
Sexual Function Preservation
Risk of Sexual Side Effects:
- PAE: Essentially nonexistent
- UroLift: Minimal risk
- Aquablation: Low risk (preserves ejaculatory function in most patients)
- Alpha-blockers: Low to moderate risk
- 5-Alpha Reductase Inhibitors: Moderate to high risk
- TURP: High risk of retrograde ejaculation (60-80%)
- Laser Surgery: Moderate risk
Hospitalization Requirements
Procedure Setting:
- PAE: Outpatient, same-day discharge
- UroLift: Outpatient procedure
- Aquablation: Outpatient or overnight stay
- Medications: No hospitalization required
- Laser Surgery: Outpatient or overnight stay
- TURP: 1-3 day hospital stay
- Open Surgery: 3-5 day hospital stay
Choosing the Right Treatment
Treatment Decision Algorithm
Step 1: Symptom Severity Assessment
- Mild symptoms (IPSS 0-7): Watchful waiting or lifestyle modifications
- Moderate symptoms (IPSS 8-19): Consider medications or minimally invasive procedures
- Severe symptoms (IPSS 20-35): Minimally invasive procedures or surgery
Step 2: Medical Therapy Trial
- Alpha-blockers for symptom relief
- 5-Alpha reductase inhibitors for prostate size reduction
- Combination therapy for comprehensive approach
Step 3: Minimally Invasive Procedures
- PAE for patients seeking effective, low-risk treatment
- UroLift for smaller prostates with preservation of sexual function
- Aquablation for patients seeking robotic precision with tissue removal
- Consider patient preferences and anatomy
Step 4: Surgical Intervention
- TURP for patients requiring definitive treatment
- Laser surgery for reduced bleeding risk
- Open surgery for very large prostates
Why PAE is Often the Preferred Choice
Optimal Balance
PAE offers the ideal combination of effectiveness and safety, providing excellent symptom relief with minimal risk and rapid recovery.
Preserves Quality of Life
Unlike surgery, PAE preserves sexual function and allows patients to return to their normal activities within days, not weeks.
Proven Results
With 93% success rates and high patient satisfaction, PAE has become the preferred choice for many men seeking BPH treatment.
Understanding Aquablation Therapy
What is Aquablation?
Aquablation therapy is an innovative, minimally invasive treatment for BPH that combines robotic technology with real-time ultrasound imaging to precisely remove prostate tissue using a high-velocity water jet. This FDA-approved procedure offers a consistent, anatomy-independent approach to treating enlarged prostate symptoms.
How Aquablation Works
- Planning Phase: Ultrasound imaging maps prostate anatomy
- Treatment Mapping: Surgeon defines treatment boundaries
- Automated Ablation: Robotic system delivers precise water jet treatment
- Hemostasis: Cautery controls bleeding if needed
- Completion: Catheter placement and recovery
Aquablation Benefits
- Consistent outcomes regardless of prostate size or shape
- Preserves ejaculatory function in most patients
- Rapid symptom improvement (typically within weeks)
- Durable results lasting years after treatment
- Lower risk of retreatment compared to some alternatives
Aquablation vs. Other Treatments
Compared to PAE:
- Requires general anesthesia vs. conscious sedation
- Involves tissue removal vs. tissue shrinkage
- Catheter required for 1-3 days vs. typically none
- Slightly longer recovery vs. same-day return to activities
- Both preserve sexual function effectively
Recovery and Results:
- 80-85% of patients experience significant symptom improvement
- Preserved ejaculatory function in approximately 90% of patients
- Return to normal activities within 1-2 weeks
- Maximum benefits typically achieved within 3 months